Thioguard informational slides
Thioguard and Glutathione Genesis.
docs.google.comThioguard mechanisms explained
Thioguard Lotion by Researched Elements: origins and mechanisms.
rumble.comThioguard endorsement: Jenny McCarthy
Jenny McCarthy feedback on Researched Elements.
rumble.comThioguard testimonials
What customers are saying about Thioguard.
researchedelements.comRecycle your burden of oxidized glutathione
A result of exhaustive research fueled by an unwavering commitment to empower and uplift our communities. With unparalleled expertise, our Thioguard Lotion™ stands as a promising ally for those seeking to enhance their health and well-being.*
- Support for sulfation
- Support for cellular rhodanese
- Access a large surface area of cells topically to quickly reduce the oxidized burden
- Support the body's conversion of inactive B12 to active B12
Why oxidized glutathione matters
Oxidized glutathione (GSSG) is the disulfide form of the antioxidant glutathione (GSH). It plays a role in maintaining the redox balance within cells. GSSG can act as a reactive oxygen species (ROS) and reactive nitrogen species (RNS) scavenger, but it can also exert inhibitory effects on certain enzymes, including SAM synthetase.
The inhibition of SAM synthetase by GSSG occurs due to the disulfide bond present in GSSG. The disulfide bond can react with and modify critical cysteine residues within the active site of SAM synthetase, thereby disrupting its enzymatic activity.
This inhibition can have significant consequences since SAM is involved in numerous methylation reactions that are essential for cellular processes, including DNA and protein methylation, neurotransmitter synthesis, and detoxification reactions. Impairment of SAM synthetase activity can disrupt these processes and have a broad impact on cellular function.
Support of your cellular processes to convert GSSG to GSH reduces the methylation inhibiting oxidized glutathione burden and provides new glutathione for use.
Taking, making and recycling glutathione
Remember there is a difference between:
- Taking glutathione: not ideal, because it oxidizes quickly and only deposits locally.
- Making glutathione: this is what Glutathione Genesis helps your cells do internally.
- Recycling glutathione: this is what Thioguard works on.
Thioguard is made by Researched Elements.
Sodium Thiosulfate Rescue of Mycotoxins
Effect of sodium thiosulphate on accumulation of metals in animals
Article.
veterinariadigital.comPublic Health Impact of Aflatoxin
Article.
medcraveonline.com| Year | Study | Evidence of benefit |
|---|---|---|
| 1987 | Fanelli et al.: Factors Related to Aflatoxin Biosynthesis | STS significantly inhibited aflatoxin production in Aspergillus cultures. Also inhibited production of several aflatoxin precursors. |
| 1995 | Karagezian et al.: Zearalenone, Brain Mitochondria and Erythrocytes | Investigated STS effects on zearalenone-induced mitochondrial membrane abnormalities, lipid peroxidation, and erythrocyte susceptibility to oxidative damage in rats. The indexed record does not provide quantitative outcomes. |
| 1997 | Karagezian et al.: Zearalenone and Rat Lymphocytes | Investigated STS correction of zearalenone-induced abnormalities in phospholipid metabolism and free-radical lipid oxidation in rat lymphocytes. |
| 2000 | Karagezian: Zearalenone and Membrane Phospholipids | STS administered intraperitoneally within 1 to 2 hours after zearalenone exposure reportedly normalized abnormalities in rat lymphocyte membrane phospholipid metabolism and lipid peroxidation. |
| 2002 | Karagyozyan: STS as an Antioxidant in Experimental Zearalenone Poisoning | STS reportedly normalized phospholipid metabolism in brain mitochondrial and microsomal membranes following zearalenone exposure. Pretreatment reportedly prevented measured membrane abnormalities. |
STS: sodium thiosulfate.